Search results for "Human metabolism"
showing 3 items of 3 documents
Transfer of aciclovir from plasma to human breast milk.
2011
Aciclovir (CAS 59277-89-3) is frequently used in herpes simplex virus diseases, but administration to lactating women occurs only rarely. Therefore, information about the pharmacokinetics of aciclovir in human breast milk is limited. The concentration in breast milk is 2 to 3 fold increased compared to plasma. The reason for this increase is unknown until now. An active transport mechanism has been assumed. The aim of this study was to prove whether the higher concentration of aciclovir in human breast milk is due to only a passive transfer. Two chambers separated by a semipermeable membrane were used. The first chamber contained plasma with aciclovir, the second chamber breast milk without…
Aripiprazole in human milk
2007
Second-generation antipsychotics are now the established first-line treatment for schizophrenia. However, there are limited data on the use of these compounds in pregnant and breastfeeding women with mental disorders. For ethical reasons, research on these subjects mostly relies on collection of single datasets of cases in order to establish treatment guidelines.
Self-Powered Measurement System for Remote Monitoring of Human Metabolism
2022
Continuous and minimally invasive measurements of metabolism are the key to the understanding and proper treatment of various pathologies. In this context, this paper deals with an innovative concept of a wireless measurement system that monitors glucose concentration and is simultaneously powered by self-measurement. The measurement system directly generates a radio transmission at a frequency proportional to the measured glucose concentration, acting de facto as a glucose concentration to time converter. In that way, a remote base station can indirectly detect glucose concentration by measuring the frequency of received radio signals. The outcome is a wireless measurement system, which us…